Wednesday, June 10, 2009
Paradigm Shifts: Pharmaceuticals Marketing - A Case Study of Elder Health Care Ltd Mumbai (ECHL) | Pharmainfo.net
FDA Drug Database , Drug Database ,KnowItAll Software,QSAR, structure activity relationship | Pharmainfo.net
Process Analytical Technology ,PAT, Process Analytical Technology impact in pharmaceutical industry | Pharmainfo.net
Friday, June 15, 2007
Total Quality Management In Pharmacy Education - Potentials
Total Quality Management In Pharmacy Education - Potentials
Lot of changes have taken place in the Pharmacy educational scenario in India since last four decades. There is a mushrooming increase in the number of Pharmacy colleges in the yester years.
Lot of changes have taken place in the Pharmacy educational scenario in India since last four decades. There is a mushrooming increase in the number of Pharmacy colleges in the yester years.
Significance of recrystallization on pharmaceutical dosage form processing
Significance of recrystallization on pharmaceutical dosage form processing
Recently in the field of Pharmaceutical Technology, great efforts are being directed towards the prefabrication of existing drug molecules in the way of solving problems related to poor water solubility, Dissolution, bioavailability, Flowability, compressibility, dosing problem, stability and toxicity.
Recently in the field of Pharmaceutical Technology, great efforts are being directed towards the prefabrication of existing drug molecules in the way of solving problems related to poor water solubility, Dissolution, bioavailability, Flowability, compressibility, dosing problem, stability and toxicity.
The role of pharmacogenomics in drug development
Pharmacogenomics is a biotechnological science that combines the techniques of medicine, pharmacology, and genomics and is concerned with developing drug therapies to compensate for genetic differences in patients which cause varied responses to a single therapeutic regimen. Patient-drug interaction is a complex trait influenced by many genes.
The role of pharmacogenomics in drug development
The role of pharmacogenomics in drug development
Tuesday, May 29, 2007
The future aspects of Prebiotics on human health: A Review
The future aspects of Prebiotics on human health: A Review
Prebiotics are short-chain carbohydrates that alter the composition, or metabolism, of the gut microbiota in a beneficial manner. It is therefore expected that prebiotics will improve health in a way similar to probiotics, whilst at the same time being cheaper, and carrying less risk and being easier to incorporate into the diet than probiotics.
Prebiotics are short-chain carbohydrates that alter the composition, or metabolism, of the gut microbiota in a beneficial manner. It is therefore expected that prebiotics will improve health in a way similar to probiotics, whilst at the same time being cheaper, and carrying less risk and being easier to incorporate into the diet than probiotics.
The role of pharmacogenomics in drug development
The role of pharmacogenomics in drug development
Pharmacogenomics is a biotechnological science that combines the techniques of medicine, pharmacology, and genomics and is concerned with developing drug therapies to compensate for genetic differences in patients which cause varied responses to a single therapeutic regimen. Patient-drug interaction is a complex trait influenced by many genes.
Without a comprehensive knowledge of all the genes that influence drug response, it is difficult to develop genetic tests that could predict a person's response to a particular drug. Pharmacogenomics is a science that examines the inherited variations in genes that dictate drug response and explores the ways these variations can be used to predict the kind of response a patient would have to a drug
Pharmacogenomics is a biotechnological science that combines the techniques of medicine, pharmacology, and genomics and is concerned with developing drug therapies to compensate for genetic differences in patients which cause varied responses to a single therapeutic regimen. Patient-drug interaction is a complex trait influenced by many genes.
Without a comprehensive knowledge of all the genes that influence drug response, it is difficult to develop genetic tests that could predict a person's response to a particular drug. Pharmacogenomics is a science that examines the inherited variations in genes that dictate drug response and explores the ways these variations can be used to predict the kind of response a patient would have to a drug
Tuesday, February 13, 2007
Drug interactions with grapefruit juice
Drug interactions with grapefruit juice
Concomitant intake with grapefruit juice increases the concentrations of many drugs in humans. The effect seems to be mediated mainly by suppression of the cytochrome P450 enzyme CYP3A4 in the small intestine wall. This results in a diminished first pass metabolism with higher bioavailability and increased maximal plasma concentrations of substrates of this enzyme. The effect was most pronounced in drugs with high first pass degradation.
Concomitant intake with grapefruit juice increases the concentrations of many drugs in humans. The effect seems to be mediated mainly by suppression of the cytochrome P450 enzyme CYP3A4 in the small intestine wall. This results in a diminished first pass metabolism with higher bioavailability and increased maximal plasma concentrations of substrates of this enzyme. The effect was most pronounced in drugs with high first pass degradation.
Orphan Diseases - An Indian Perspective
Orphan Diseases - An Indian Perspective:
Diseases which manifest in patient populations representing at the maximum 6-8% of the world population are defined as rare diseases. 1 They are pathologies whose incidence at birth is less than 1 in 2000. 50% of these appear when the sufferer has reached adult age. Today there are over 5000 rare diseases listed in the world with five new rare diseases being described every week in the medical literature.
Diseases which manifest in patient populations representing at the maximum 6-8% of the world population are defined as rare diseases. 1 They are pathologies whose incidence at birth is less than 1 in 2000. 50% of these appear when the sufferer has reached adult age. Today there are over 5000 rare diseases listed in the world with five new rare diseases being described every week in the medical literature.
Tuesday, February 06, 2007
Pharmacogenomics: Impact on Drug Response and Applications to Infectious Diseases Management
Pharmacogenomics: Impact on Drug Response and Applications to Infectious Diseases Management
The impact of pharmacogenomics on the prevention, diagnosis, and treatment of infectious diseases is discussed. The application of pharmacogenomics to infectious diseases requires consideration of the genomes of both the pathogen and the host.
The impact of pharmacogenomics on the prevention, diagnosis, and treatment of infectious diseases is discussed. The application of pharmacogenomics to infectious diseases requires consideration of the genomes of both the pathogen and the host.
Specialized chronotherapeutic drug delivery systems
Specialized chronotherapeutic drug delivery systems
In the field of modified release, matching of drug release to the body’s circadian rhythms have been fundamental strategies involves for selecting a new drug delivery system which increase the efficacy and safety of drugs by proportioning their peak plasma concentrations during the 24 hours in synchrony with biological rhythm.
In the field of modified release, matching of drug release to the body’s circadian rhythms have been fundamental strategies involves for selecting a new drug delivery system which increase the efficacy and safety of drugs by proportioning their peak plasma concentrations during the 24 hours in synchrony with biological rhythm.
Novel Approaches In Vaccines Delivery
Novel Approaches In Vaccines Delivery
Oral vaccination of animals and man, to provide effective mucosal and/or systemic immunity, is largely ineffective. This is due mainly to the very small quantity of antigen that survives degradation in the intestine and that crosses the intestinal wall.
Oral vaccination of animals and man, to provide effective mucosal and/or systemic immunity, is largely ineffective. This is due mainly to the very small quantity of antigen that survives degradation in the intestine and that crosses the intestinal wall.
Saturday, February 03, 2007
Six Sigma: A measure of goodness in Quality Management System
Six Sigma: A measure of goodness in Quality Management System
Six Sigma (6σ) is a methodology to manage process variations that cause defects. It can be defined as a rigorous and disciplined methodology that utilizes data and statistical analysis to measure and improve a company’s operational performance, practices and systems. Six Sigma identifies and prevents defects in manufacturing and service-related processes.
Six Sigma (6σ) is a methodology to manage process variations that cause defects. It can be defined as a rigorous and disciplined methodology that utilizes data and statistical analysis to measure and improve a company’s operational performance, practices and systems. Six Sigma identifies and prevents defects in manufacturing and service-related processes.
Sunday, January 28, 2007
Super Critical Fluid Chromatography : Fundamentals and Applications
Super Critical Fluid Chromatography : Fundamentals and Applications
When supercritical fluid chromatography was first developed in 1960, it was considered as a science fiction chromatography and a revolutionary separation technique. But its reputation has slowly ebbed over the years and it is now moving forward by leaps and bounds as a stable Analytical Method with many advantages over the existing chromatographic methods.
When supercritical fluid chromatography was first developed in 1960, it was considered as a science fiction chromatography and a revolutionary separation technique. But its reputation has slowly ebbed over the years and it is now moving forward by leaps and bounds as a stable Analytical Method with many advantages over the existing chromatographic methods.
Analysis of preservatives in pharmaceutical products
Analysis of preservatives in pharmaceutical products
Preservatives are substances that commonly added to various foods and pharmaceutical products in order to prolong their shelf life. The addition of preservatives to such products, especially to those that have higher water content, is essential for avoiding alteration and degradation by microorganisms during storage
Preservatives are substances that commonly added to various foods and pharmaceutical products in order to prolong their shelf life. The addition of preservatives to such products, especially to those that have higher water content, is essential for avoiding alteration and degradation by microorganisms during storage
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